The bank provides commercial and general banking services. It is a market leader in debt equity, corporate investment banking, consumer and retail banking, agricultural finance and treasury services.

National Bank of Pakistan has developed a wide range of consumer products, to enhance business, meet the needs of different segments of society and fulfill its social responsibilities. Some schemes are specifically designed for low to middle income segments of the population. It has implemented special credit schemes such as micro finance for agriculture, business and industries, responsible for good loans for students, self-employment scheme for the unemployed and public transport scheme. The bank has expanded its products and services to include Islamic banking products that are compatible with Islamic Sharia. It also developed a money transfer service for expatriate Pakistanis to bring their money back to Pakistan. Customer Social Responsibility is a new division that provides social services for education, health and women's empowerment.